@prefix pots: . @prefix cascade: . @prefix owl: . @prefix rdf: . @prefix rdfs: . @prefix xsd: . @prefix dct: . @prefix fhir: . @prefix sct: . @prefix loinc: . @prefix ucum: . @prefix prov: . # ============================================================================ # Ontology Metadata # ============================================================================ a owl:Ontology ; owl:imports ; dct:title "Cascade Protocol POTS Check Ontology"@en ; dct:description "Vocabulary for POTS (Postural Orthostatic Tachycardia Syndrome) home screening checks using the NASA Lean Test protocol"@en ; dct:creator "Cascade Agentic Labs" ; dct:created "2025-10-31"^^xsd:date ; dct:modified "2026-02-26"^^xsd:date ; owl:versionInfo "1.4" ; rdfs:comment "Layer 2 domain-specific vocabulary for POTS Check app. Defines the POTS screening test protocol, raw measurement classes, and computed results. Describes consumer-generated wellness data from guided orthostatic screening checks performed with Apple Watch and iPhone."@en ; rdfs:seeAlso . # ============================================================================ # Core Classes # ============================================================================ pots:POTSCheckResult a owl:Class ; rdfs:label "POTS Check Result"@en ; rdfs:comment "Complete result bundle from a guided home orthostatic screening check using Apple Watch heart rate monitoring and iPhone posture detection"@en ; rdfs:subClassOf [ a owl:Restriction ; owl:onProperty pots:date ; owl:cardinality 1 ] ; rdfs:subClassOf [ a owl:Restriction ; owl:onProperty pots:protocol ; owl:cardinality 1 ] ; rdfs:subClassOf prov:Entity . pots:HeartRateMeasurement a owl:Class ; rdfs:label "Heart Rate Measurement"@en ; rdfs:comment "Timed heart rate observation captured during standing phase"@en ; rdfs:subClassOf fhir:Observation . pots:BloodPressureMeasurement a owl:Class ; rdfs:label "Blood Pressure Measurement"@en ; rdfs:comment "Timed blood pressure observation (systolic/diastolic) captured during check"@en ; rdfs:subClassOf fhir:Observation . pots:SymptomEvent a owl:Class ; rdfs:label "Symptom Event"@en ; rdfs:comment "User-reported symptom captured during the standing phase of the check"@en . pots:PostureStability a owl:Class ; rdfs:label "Posture Stability Sample"@en ; rdfs:comment "Posture quality measurement from Core Motion sensors during standing phase"@en . # ============================================================================ # Test Protocol Classes # ============================================================================ pots:TestProtocol a owl:Class ; rdfs:label "Test Protocol"@en ; rdfs:comment "Standardized orthostatic test protocol"@en . pots:NASALean a pots:TestProtocol ; rdfs:label "NASA Lean Test"@en ; rdfs:comment "10 minutes supine followed by 10 minutes standing against wall, as specified by NASA research protocols"@en ; rdfs:seeAlso . # ============================================================================ # Data Properties - Test Metadata # ============================================================================ pots:date a owl:DatatypeProperty ; rdfs:label "Check Date"@en ; rdfs:comment "ISO 8601 timestamp when the check was performed"@en ; rdfs:domain pots:POTSCheckResult ; rdfs:range xsd:dateTime . pots:protocol a owl:DatatypeProperty ; rdfs:label "Test Protocol"@en ; rdfs:comment "Protocol used for the check (currently only 'nasaLean')"@en ; rdfs:domain pots:POTSCheckResult ; rdfs:range xsd:string . pots:baselineDurationSeconds a owl:DatatypeProperty ; rdfs:label "Baseline Duration (seconds)"@en ; rdfs:comment "Duration of the supine baseline phase in seconds (typically 600 for 10 minutes)"@en ; rdfs:domain pots:POTSCheckResult ; rdfs:range xsd:integer . pots:uprightDurationSeconds a owl:DatatypeProperty ; rdfs:label "Upright Duration (seconds)"@en ; rdfs:comment "Duration of the standing phase in seconds (typically 600 for 10 minutes)"@en ; rdfs:domain pots:POTSCheckResult ; rdfs:range xsd:integer . # ============================================================================ # Data Properties - Heart Rate # ============================================================================ pots:supineHeartRate a owl:ObjectProperty ; rdfs:label "Supine Heart Rate"@en ; rdfs:comment "Baseline heart rate observation from final 2 minutes of supine phase"@en ; rdfs:domain pots:POTSCheckResult ; rdfs:range pots:HeartRateMeasurement ; owl:equivalentProperty sct:78564009 . # Heart rate at rest pots:standingHeartRates a owl:ObjectProperty ; rdfs:label "Standing Heart Rates"@en ; rdfs:comment "Ordered list of heart rate measurements captured during standing phase"@en ; rdfs:domain pots:POTSCheckResult ; rdfs:range rdf:List . pots:recoveryHeartRate a owl:DatatypeProperty ; rdfs:label "Recovery Heart Rate"@en ; rdfs:comment "Optional heart rate measurement after returning to supine position (v1.1+)"@en ; rdfs:domain pots:POTSCheckResult ; rdfs:range xsd:double . pots:maxHeartRateDelta a owl:DatatypeProperty ; rdfs:label "Maximum Heart Rate Delta"@en ; rdfs:comment "Pre-computed maximum heart rate increase from baseline using 30-second rolling window average during standing phase (v1.2+)"@en ; rdfs:domain pots:POTSCheckResult ; rdfs:range xsd:double . # ============================================================================ # Data Properties - Blood Pressure # ============================================================================ pots:supineBloodPressure a owl:ObjectProperty ; rdfs:label "Supine Blood Pressure"@en ; rdfs:comment "Blood pressure measurement taken during or just before supine phase"@en ; rdfs:domain pots:POTSCheckResult ; rdfs:range pots:BloodPressureMeasurement . pots:standingBloodPressures a owl:ObjectProperty ; rdfs:label "Standing Blood Pressures"@en ; rdfs:comment "List of blood pressure measurements captured at specific minutes during standing phase (typically minutes 1, 3, 5, 7, 10)"@en ; rdfs:domain pots:POTSCheckResult ; rdfs:range rdf:List . # ============================================================================ # Data Properties - Symptoms # ============================================================================ pots:symptomEvents a owl:ObjectProperty ; rdfs:label "Symptom Events"@en ; rdfs:comment "List of symptoms reported by user during the check"@en ; rdfs:domain pots:POTSCheckResult ; rdfs:range rdf:List . pots:symptom a owl:DatatypeProperty ; rdfs:label "Symptom Type"@en ; rdfs:comment "Type of symptom experienced (e.g., 'Dizziness', 'Palpitations')"@en ; rdfs:domain pots:SymptomEvent ; rdfs:range xsd:string . pots:notes a owl:DatatypeProperty ; rdfs:label "Symptom Notes"@en ; rdfs:comment "Optional user-provided notes describing the symptom (max 100 characters)"@en ; rdfs:domain pots:SymptomEvent ; rdfs:range xsd:string . # ============================================================================ # Data Properties - Clinical Flags # ============================================================================ pots:potsThresholdMet a owl:DatatypeProperty ; rdfs:label "POTS Threshold Met"@en ; rdfs:comment "True if heart rate increase meets POTS screening criteria (age-adjusted: >=30 bpm for adults 20+, >=40 bpm for pediatric 13-19)"@en ; rdfs:domain pots:POTSCheckResult ; rdfs:range xsd:boolean . pots:orthostaticHypotensionSuspected a owl:DatatypeProperty ; rdfs:label "Orthostatic Hypotension Suspected"@en ; rdfs:comment "True if blood pressure drop suggests orthostatic hypotension (systolic >=20 mmHg or diastolic >=10 mmHg drop)"@en ; rdfs:domain pots:POTSCheckResult ; rdfs:range xsd:boolean . pots:orthostaticHypertensionSuspected a owl:DatatypeProperty ; rdfs:label "Orthostatic Hypertension Suspected"@en ; rdfs:comment "True if blood pressure increase suggests orthostatic hypertension (systolic >=20 mmHg increase) (v1.1+)"@en ; rdfs:domain pots:POTSCheckResult ; rdfs:range xsd:boolean . pots:isIncomplete a owl:DatatypeProperty ; rdfs:label "Is Incomplete"@en ; rdfs:comment "True if the check was terminated early or did not complete all phases"@en ; rdfs:domain pots:POTSCheckResult ; rdfs:range xsd:boolean . pots:earlyTerminationReason a owl:DatatypeProperty ; rdfs:label "Early Termination Reason"@en ; rdfs:comment "Human-readable reason why the check was terminated early (v1.1+)"@en ; rdfs:domain pots:POTSCheckResult ; rdfs:range xsd:string . # ============================================================================ # Data Properties - Posture Quality (v1.1+) # ============================================================================ pots:postureQualityScore a owl:DatatypeProperty ; rdfs:label "Posture Quality Score"@en ; rdfs:comment "Letter grade (A-D) indicating overall posture stability during standing phase (v1.1+)"@en ; rdfs:domain pots:POTSCheckResult ; rdfs:range xsd:string . pots:movementArtifactPercentage a owl:DatatypeProperty ; rdfs:label "Movement Artifact Percentage"@en ; rdfs:comment "Percentage of standing phase with excessive movement artifacts (0.0 to 100.0) (v1.1+)"@en ; rdfs:domain pots:POTSCheckResult ; rdfs:range xsd:double . pots:postureStability a owl:ObjectProperty ; rdfs:label "Posture Stability"@en ; rdfs:comment "List of posture stability measurements from Core Motion during standing phase (v1.1+)"@en ; rdfs:domain pots:POTSCheckResult ; rdfs:range rdf:List . pots:isStable a owl:DatatypeProperty ; rdfs:label "Is Stable"@en ; rdfs:comment "Boolean indicating whether posture was stable at this timestamp"@en ; rdfs:domain pots:PostureStability ; rdfs:range xsd:boolean . pots:stabilityScore a owl:DatatypeProperty ; rdfs:label "Stability Score"@en ; rdfs:comment "Numerical stability score from 0.0 (unstable) to 1.0 (perfectly stable)"@en ; rdfs:domain pots:PostureStability ; rdfs:range xsd:double . # ============================================================================ # Data Properties - User Context (v1.2+) # ============================================================================ pots:userAgeAtTest a owl:DatatypeProperty ; rdfs:label "User Age at Test"@en ; rdfs:comment "User's age in years at the time of the check, used for age-based threshold calculation (v1.2+)"@en ; rdfs:domain pots:POTSCheckResult ; rdfs:range xsd:integer . # ============================================================================ # Data Properties - Timing # ============================================================================ pots:atSeconds a owl:DatatypeProperty ; rdfs:label "Seconds Since Standing"@en ; rdfs:comment "Time offset in seconds from the start of the standing phase"@en ; rdfs:range xsd:integer . pots:secondsSinceStand a owl:DatatypeProperty ; rdfs:label "Seconds Since Stand"@en ; rdfs:comment "Time offset in seconds from the moment the user stood up. Used in standingHeartRates and standingBloodPressures list items for temporal positioning."@en ; rdfs:range xsd:double . pots:timestampSeconds a owl:DatatypeProperty ; rdfs:label "Timestamp Seconds"@en ; rdfs:comment "Absolute timestamp in seconds, used in SymptomEvent items for precise event timing."@en ; rdfs:range xsd:double . # ============================================================================ # Apple Health Import Properties (v1.3) # ============================================================================ pots:importedBloodPressureHistory a owl:ObjectProperty ; rdfs:label "Imported Blood Pressure History"@en ; rdfs:comment "Collection of blood pressure readings imported from Apple Health for longitudinal context. Each item is a fhir:Observation with systolic/diastolic components."@en ; rdfs:domain pots:POTSCheckResult ; rdfs:range rdf:List . pots:importedHRVHistory a owl:ObjectProperty ; rdfs:label "Imported HRV History"@en ; rdfs:comment "Collection of HRV readings imported from Apple Health for longitudinal context. Each item is a fhir:Observation with value in milliseconds."@en ; rdfs:domain pots:POTSCheckResult ; rdfs:range rdf:List . pots:averageImportedBloodPressure a owl:DatatypeProperty ; rdfs:label "Average Imported Blood Pressure"@en ; rdfs:comment "Computed average of imported blood pressure readings from Apple Health, formatted as 'systolic/diastolic' string."@en ; rdfs:domain pots:POTSCheckResult ; rdfs:range xsd:string . pots:averageImportedHRV a owl:DatatypeProperty ; rdfs:label "Average Imported HRV"@en ; rdfs:comment "Computed average of imported HRV readings from Apple Health (ms)."@en ; rdfs:domain pots:POTSCheckResult ; rdfs:range xsd:double . # ============================================================================ # V2 Test Configuration & Patient Context (v1.4+) # ============================================================================ pots:baselineDurationMinutes a owl:DatatypeProperty ; rdfs:label "Baseline Duration (minutes)"@en ; rdfs:comment "User-selected supine baseline duration in whole minutes. One of: 5, 10, or 15. Captures the deliberate configuration choice (distinct from pots:baselineDurationSeconds which records actual elapsed time). Values below 10 minutes carry a clinical advisory per Bateman Horne Center guidance. (v1.4+)"@en ; rdfs:domain pots:POTSCheckResult ; rdfs:range xsd:integer . pots:testNotes a owl:DatatypeProperty ; rdfs:label "Test Notes"@en ; rdfs:comment "Optional free-text notes entered by the patient about this check session (e.g., current symptoms, recent activity, medication timing). Maximum 500 characters. Distinct from pots:notes which is scoped to individual pots:SymptomEvent items. (v1.4+)"@en ; rdfs:domain pots:POTSCheckResult ; rdfs:range xsd:string . pots:bpProvided a owl:DatatypeProperty ; rdfs:label "Blood Pressure Provided"@en ; rdfs:comment "True if blood pressure cuff data was entered during this check session. False if the user proceeded without a blood pressure cuff. Used by result views and PDF generator to gate BP-dependent sections and display appropriate limitation warnings. (v1.4+)"@en ; rdfs:domain pots:POTSCheckResult ; rdfs:range xsd:boolean . # ============================================================================ # Proportional Pulse Pressure — Per-Minute Values (v1.4+) # ============================================================================ # PPP = (SBP - DBP) / SBP. Values stored as ratios (0.0 to 1.0). # Clinical reference: PPP < 0.25 (25%) may indicate failure to constrict # on standing (Bateman Horne Center clinical guidance). # Predicates are absent when no BP reading exists at that timepoint. # Timepoints mirror the standing BP collection schedule: 1, 3, 5, 7, 10 minutes. pots:pppMinute1 a owl:DatatypeProperty ; rdfs:label "Proportional Pulse Pressure at 1 Minute"@en ; rdfs:comment "Proportional Pulse Pressure ratio (SBP-DBP)/SBP at 1 minute of standing. Stored as a decimal ratio 0.0-1.0. Absent if no blood pressure reading was taken at this timepoint. Reference: values >= 0.25 (25%) are considered normal per Bateman Horne Center clinical guidance. (v1.4+)"@en ; rdfs:domain pots:POTSCheckResult ; rdfs:range xsd:decimal . pots:pppMinute3 a owl:DatatypeProperty ; rdfs:label "Proportional Pulse Pressure at 3 Minutes"@en ; rdfs:comment "Proportional Pulse Pressure ratio (SBP-DBP)/SBP at 3 minutes of standing. Stored as a decimal ratio 0.0-1.0. Absent if no blood pressure reading was taken at this timepoint. (v1.4+)"@en ; rdfs:domain pots:POTSCheckResult ; rdfs:range xsd:decimal . pots:pppMinute5 a owl:DatatypeProperty ; rdfs:label "Proportional Pulse Pressure at 5 Minutes"@en ; rdfs:comment "Proportional Pulse Pressure ratio (SBP-DBP)/SBP at 5 minutes of standing. Stored as a decimal ratio 0.0-1.0. Absent if no blood pressure reading was taken at this timepoint. (v1.4+)"@en ; rdfs:domain pots:POTSCheckResult ; rdfs:range xsd:decimal . pots:pppMinute7 a owl:DatatypeProperty ; rdfs:label "Proportional Pulse Pressure at 7 Minutes"@en ; rdfs:comment "Proportional Pulse Pressure ratio (SBP-DBP)/SBP at 7 minutes of standing. Stored as a decimal ratio 0.0-1.0. Absent if no blood pressure reading was taken at this timepoint. (v1.4+)"@en ; rdfs:domain pots:POTSCheckResult ; rdfs:range xsd:decimal . pots:pppMinute10 a owl:DatatypeProperty ; rdfs:label "Proportional Pulse Pressure at 10 Minutes"@en ; rdfs:comment "Proportional Pulse Pressure ratio (SBP-DBP)/SBP at 10 minutes of standing. Stored as a decimal ratio 0.0-1.0. Absent if no blood pressure reading was taken at this timepoint. (v1.4+)"@en ; rdfs:domain pots:POTSCheckResult ; rdfs:range xsd:decimal . # ============================================================================ # Alignment with Healthcare Standards # ============================================================================ # SNOMED CT Mappings # - Heart rate: sct:364075005 (Heart rate) # - Supine position: sct:40199007 (Supine body position) # - Standing position: sct:10904000 (Orthostatic body position) # - POTS: sct:703273007 (Postural orthostatic tachycardia syndrome) # - Orthostatic hypotension: sct:28651003 # LOINC Mappings # - Heart rate: loinc:8867-4 (Heart rate) # - Systolic BP: loinc:8480-6 (Systolic blood pressure) # - Diastolic BP: loinc:8462-4 (Diastolic blood pressure) # FHIR Observation Pattern # All heart rate and blood pressure measurements use fhir:Observation structure # with fhir:code, fhir:valueQuantity, and ucum: units # ============================================================================ # Notes # ============================================================================ # Data Classification: Consumer wellness data (non-diagnostic) # Target Age Range: 13+ (COPPA compliant) # Devices: Apple Watch (heart rate), iPhone (posture tracking, UI) # Protocol: NASA Lean Test (10 min supine + 10 min standing against wall) # Diagnostic Disclaimer: Results are for informational purposes only and should # be discussed with a healthcare provider. This is NOT a medical diagnostic tool. # ============================================================================ # Changelog # ============================================================================ # v1.4 (2026-02-26): Added pots:baselineDurationMinutes (user-selected baseline # duration in whole minutes, distinct from pots:baselineDurationSeconds). # Added pots:testNotes (free-text patient notes on the result, distinct from # per-symptom pots:notes). Added pots:bpProvided (boolean flag for BP cuff # presence). Added per-minute PPP predicates pots:pppMinute1, pots:pppMinute3, # pots:pppMinute5, pots:pppMinute7, pots:pppMinute10 for Proportional Pulse # Pressure values (ratio 0.0-1.0) at each standard BP timepoint. # v1.3 (2026-02-10): Added timing properties (secondsSinceStand, timestampSeconds) # for fine-grained temporal resolution in measurement lists. Added Apple Health # import properties (importedBloodPressureHistory, importedHRVHistory, # averageImportedBloodPressure, averageImportedHRV) for longitudinal context. # Renamed postureStabilitySamples to postureStability to match app serializer. # v1.2 (2025-12-15): Added userAgeAtTest, maxHeartRateDelta. # v1.1 (2025-11-15): Added recoveryHeartRate, orthostaticHypertensionSuspected, # earlyTerminationReason, posture quality (postureQualityScore, # movementArtifactPercentage, PostureStability class). # v1.0 (2025-10-31): Initial release. POTSCheckResult, HeartRateMeasurement, # BloodPressureMeasurement, SymptomEvent, TestProtocol, NASALean.